ovalbumin specific IgE
卵清蛋白(OVA)是在蛋清中发现的主要蛋白,约占总蛋白的55%。卵清蛋白与丝氨酸超家族的序列和三维有同源性,但与大多数丝氨酸不同,它不是丝氨酸蛋白酶抑制剂。它有385个氨基酸组成,其相对分子质量为42.7 kDa。卵清蛋白从细胞中分泌出来,以内部信号序列(残基21-47)为目标,而不是其他分泌蛋白中常见的N端信号序列。
可检测样本中小鼠的OVA-sIgE,且与其类似物无明显交叉反应。
由于实验操作条件的不同( 如操作者、移液技术、洗板技术和稳定条件等),标准曲线的OD值会有所差异。以下数据和曲线仅供参考,实验者需根据自己的实验建立标准曲线。
板内变异系数小于10%,板间变异系数小于10%
注:ELISA试剂盒检测范围等数据,因检测样本 的不同而调整,实际数据以随货说明书为准。
Xiao-qing-long-tang ameliorates OVA-induced allergic rhinitis by inhibiting ILC2s through the IL-33/ST2 and JAK/STAT pathways
Rank: IF 6.7
Journal: Phytomedicine
Year: 2023
DOI: 10.1016/j.phymed.2023.155012
Neonatal LPS Administered Before Sensitization Reduced the Number of Inflammatory Monocytes and Abrogated the Development of OVA-Induced Th2 Allergic Airway Inflammation
Rank: IF 5.7
Journal: Frontiers in Immunology
Year: 2021
DOI: 10.3389/fimmu.2021.725906
Chemical constituents from the flowers of Inula japonica and their anti-inflammatory activity
Rank: IF 4.8
Journal: Journal of Ethnopharmacology
DOI: 10.1016/j.jep.2023.117052
Xiaoqinglong decoction improves allergic rhinitis by inhibiting NLRP3-mediated pyroptosis in BALB/C mice
DOI: 10.1016/j.jep.2023.117490
Xiaoqinglong decoction mitigates nasal inflammation and modulates gut microbiota in allergic rhinitis mice
Rank: IF 4
Journal: Frontiers in Microbiology
Year: 2024
DOI: 10.3389/fmicb.2024.1290985
Zinc supplement reduces allergic responses through modulating the p38 MAPK pathway activation in an allergic rhinitis mouse model
Rank: IF 3.6
Journal: Journal of Trace Elements in Medicine and Biology
Year: 2022
DOI: 10.1016/j.jtemb.2022.127094
Knockdown of miR2055p alleviates the inflammatory response in allergic rhinitis by targeting Bcell lymphoma 6
Rank: IF 3.4
Journal: Molecular Medicine Reports
DOI: 10.3892/mmr.2021.12458
Gentiopicroside ameliorates ovalbumin-induced airway inflammation in a mouse model of allergic asthma via regulating SIRT1/NF-κB signaling pathway.
Rank: IF 3.3
Journal: Pulmonary Pharmacology & Therapeutics
DOI: 10.1016/j.pupt.2021.102034
Monotropein Alleviates Ovalbumin-Induced Asthma in Mouse Model by Inhibiting AKT/NF-κB Pathway
Rank: IF 2.5
Journal: International Archives of Allergy and Immunology
DOI: 10.1159/000535450
Knockdown of Cadherin 26 Prevents the Inflammatory Responses of Allergic Rhinitis
Rank: IF 2.2
Journal: Laryngoscope
DOI: 10.1002/lary.30380