CSIF; IL10A; TGIF; Cytokine Synthesis Inhibitory Factor
白细胞介素10(IL-10)是一种免疫抑制细胞因子,由多种哺乳动物细胞类型产生,包括巨噬细胞、单核细胞、T细胞、B细胞和角质细胞。IL-10抑制促炎症细胞因子的表达,如IL-1和TNFα。与IL-4一样,IL-10能增强体液免疫反应,减弱细胞介导的免疫反应。人的IL-10在小鼠细胞上有活性,但小鼠的IL-10在人的细胞上没有活性。
可检测样本中小鼠的IL-10,且与其类似物无明显交叉反应。
由于实验操作条件的不同( 如操作者、移液技术、洗板技术和稳定条件等),标准曲线的OD值会有所差异。以下数据和曲线仅供参考,实验者需根据自己的实验建立标准曲线。
注意:本图仅供参考,应以同次试验标准品所绘标准曲线计算标本含量。
板内变异系数小于10%,板间变异系数小于10%
在选取的健康小鼠血清、血浆、细胞培养上清中加入3个不同浓度水平的小鼠IL-10,计算回收率
分别在选取的4份健康小鼠血清、血浆、细胞培养上清中加入高浓度小鼠IL-10,在标准曲线动力学范围内进行稀释,评估线性。
注:ELISA试剂盒检测范围等数据,因检测样本 的不同而调整,实际数据以随货说明书为准。
Structural characterization of polysaccharide from yellow sweet potato and ameliorates DSS-induced mice colitis by active GPR41/MEK/ERK 1/2 signaling pathway.
Rank: IF 8.2
Journal: International Journal of Biological Macromolecules
Year: 2021
DOI: 10.1016/j.ijbiomac.2021.09.175
Selenium Nanoparticles-Enriched Lactobacillus casei ATCC 393 Prevents Cognitive Dysfunction in Mice Through Modulating Microbiota-Gut-Brain Axis
Rank: IF 8
Journal: International Journal of Nanomedicine
Year: 2022
DOI: 10.2147/IJN.S374024
Evaluation of remodeling and regeneration of electrospun PCL/fibrin vascular grafts in vivo
Rank: IF 7.9
Journal: Materials Science & Engineering C-Materials for Biological Applications
Year: 2020
DOI: 10.1016/j.msec.2020.111441
Nuanxinkang Protects Against Ischemia/Reperfusion-Induced Heart Failure Through Regulating IKKβ/IκBα/NF-κB-Mediated Macrophage Polarization
Journal: Phytomedicine
DOI: 10.1016/j.phymed.2022.154093
Lactobacillus casei ATCC 393 combined with vasoactive intestinal peptidealleviates dextran sodium sulfate-induced ulcerative colitis in C57BL/6mice via NF-κB and Nrf2 signaling pathways
Rank: IF 7.5
Journal: Biomedicine & Pharmacotherapy
Year: 2023
DOI: 10.1016/j.biopha.2023.115033
Inhibition of DRP1-dependent mitochondrial fission by Mdivi-1 alleviates atherosclerosis through the modulation of M1 polarization
Rank: IF 7.4
Journal: Journal of Translational Medicine
DOI: 10.1186/s12967-023-04270-9
MiR-34a-5p/Sirt1 axis: A novel pathway for puerarin-mediated hepatoprotection against benzo(a)pyrene
Journal: Free Radical Biology and Medicine
DOI: 10.1016/j.freeradbiomed.2022.05.006
Oxidative stress-induced aberrant lipid metabolism is an important causal factor for dysfunction of immunocytes from patients with systemic lupus erythematosus.
DOI: 10.1016/j.freeradbiomed.2020.12.006
Lactate-driven macrophage polarization in the inflammatory microenvironment alleviates intestinal inflammation
Rank: IF 7.3
Journal: Frontiers In Immunology
DOI: 10.3389/fimmu.2022.1013686
Occlusion preconditioned mice are resilient to hypobaric hypoxia-induced myocarditis and arrhythmias due to enhanced immunomodulation, metabolic homeostasis, and antioxidants defense
Journal: Frontiers in Immunology
DOI: 10.3389/fimmu.2023.1124649