17B-Estradiol; Oestradiol; Beta-Estradiol
雌二醇(Estradiol,E2),亦称“动情素”、“求偶素”。化学式 C18H24O2, 分子量为 272.38,有α,β两种类型,雌激素的一种。含量最多,活性也最 强。由卵巢内卵泡的颗粒细胞分泌,其代谢物是雌酮及雌三醇。含 18 个碳 原子。其靶器官为子宫、阴道、输卵管和垂体。可作为一种为经皮肤吸收的 雌激素治疗剂。雌激素能促使细胞合成 DNA、RNA 和相应组织内各种不同 的蛋白质。
可检测样本中大鼠的E2,且与其类似物无明显交叉反应。
由于实验操作条件的不同( 如操作者、移液技术、洗板技术和稳定条件等),标准曲线的OD值会有所差异。以下数据和曲线仅供参考,实验者需根据自己的实验建立标准曲线。
注意:本图仅供参考,应以同次试验标准品所绘标准曲线计算标本含量。
板内变异系数小于10%,板间变异系数小于10%
在选取的健康大鼠血清、血浆、细胞培养上清中加入3个不同浓度水平的大鼠E2,计算回收率
分别在选取的4份健康大鼠血清、血浆、细胞培养上清中加入高浓度大鼠E2,在标准曲线动力学范围内进行稀释,评估线性。
注:ELISA试剂盒检测范围等数据,因检测样本 的不同而调整,实际数据以随货说明书为准。
Effects of Bisphenol A on reproductive toxicity and gut microbiota dysbiosis in male rats
Rank: IF 6.2
Journal: Ecotoxicology and Environmental Safety
Year: 2022
DOI: 10.1016/j.ecoenv.2022.113623
Exploring the mechanism of Semen Cuscutae processed with salt solution in improving kidney deficiency miscarriage based on serum pharmacochemistry and network pharmacology
Rank: IF 5.3
Journal: Arabian Journal of Chemistry
Year: 2023
DOI: 10.1016/j.arabjc.2023.105456
Bu-shen-zhu-yun decoction inhibits granulosa cell apoptosis in rat polycystic ovary syndrome through estrogen receptor α-mediated PI3K/AKT/mTOR pathway
Rank: IF 4.8
Journal: Journal of Ethnopharmacology
Year: 2021
DOI: 10.1016/j.jep.2021.114862
Characterization of the volatile profile and its estrogenic activity in Kadsura coccinea fruit.
DOI: 10.1016/j.jep.2023.116341
A Chinese herbs complex ameliorates gut microbiota dysbiosis induced by intermittent cold exposure in female rats
Rank: IF 4
Journal: Frontiers in Microbiology
DOI: 10.3389/fmicb.2022.1065780
Dietary α-Linolenic Acid-Rich Flaxseed Oil Exerts Beneficial Effects on Polycystic Ovary Syndrome Through Sex Steroid Hormones—Microbiota—Inflammation Axis in Rats
Rank: IF 3.9
Journal: Frontiers in Endocrinology
Year: 2020
DOI: 10.3389/fendo.2020.00284
An integrated study of hormone-related sarcopenia for modeling and comparative transcriptome in rats
DOI: 10.3389/fendo.2023.1073587
To explore the mechanism of acupoint application in the treatment of primary dysmenorrhea by 16S rDNA sequencing and metabolomics
Year: 2024
DOI: 10.3389/fendo.2024.1397402
Peptide TQS169 prevents osteoporosis in rats by enhancing osteogenic differentiation and calcium absorption
Rank: IF 3.8
Journal: Journal of Functional Foods
Year: 2018
DOI: 10.1016/j.jff.2018.08.021
Placental mesenchymal stem cells ameliorate NLRP3 inflammasome-induced ovarian insufficiency by modulating macrophage M2 polarization
Journal: Journal of Ovarian Research
DOI: 10.1186/s13048-023-01136-y